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developed a PKM2 allosteric converter (PAC) comprising three functional modules: (1) an allosteric effector module featuring a serine-based motif that bound to PKM2 at Leu-353 and Asp-354, inducing dimer-to-tetramer conversion
[Abstract]2025 Dec 22
Pharmacists can also provide guidance about pen use, storage problems, or device replacement if a pen does not work correctly
Side effects, including nausea (44% vs 44%), constipation (28% vs 29%), diarrhea (24% vs 23%), and vomiting (15% vs 21%), were similar between groups and mainly occurred during the therapy titration phase
Noguchi, R
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